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BPS and associated diseases: literature on systemic lupus erythematosus (SLE), lupus cystitis and BPS  


ESSIC uses the name bladder pain syndrome (BPS) instead of interstitial cystitis (IC) and/or painful bladder syndrome (PBS):
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general information on systemic lupus erythematosus
  • Systemic lupus erythematosus.
    Rahman A, Isenberg DA. N Engl J Med 2008;358:929-39
    • a great review on genetic and epidemiologic factors, autoantibodies, tissue damage by autoantibodies, the role of T cells, source of the autoantigens, cytokines and implications for treatment
relationship between BPS and SLE
  • Interstitial cystitis and systemic lupus erythematosus in a 20-year old woman.
    do Socorro Teixeira Moreira Almeida M, Carvalho LL, Carvalho AG, et al. J Rheumatol Int 2008 Aug 12. (Epub ahead of print] PMID: 18696074
    • a case report of a 20-year-old woman with systemic lupus erythematosus; she presented with dysuria, urinary frequency and suprapubic pain and was found to have a interstitial cystitis
  • Lupus cystitis on Ga-67 scans.
    Lin WY, Lan JL, Wang SJ. Clin Nucl Med 2000;25:737
    • a 46-year-old woman with systemic lupus erythematosus had hematuria, fever, and proteinuria. She was transferred to the nuclear medicine department for evaluation of the disease activity of lupus nephritis. A Ga-67 scan showed increased radioactivity in both kidneys. Active nephritis was suggested. Furthermore, increased Ga-67 uptake in the wall of the urinary bladder was also noted. Lupus cystitis was indicated. A bladder biopsy confirmed the diagnosis.
  • Involvement of the urinary bladder in systemic lupus erythematosus. A pathologic study.
    Alarcon-Segovia D, Abud-Mendoza C, Reyes-Gutierrez E, et al. J Rheumatol 1984;11:208-10
    • urinary bladder histologic changes were found in 16 of 35 necropsies from systemic lupus erythematosus (SLE) patients; these included interstitial cystitis (n = 11), hemorrhage (n = 9), congestion (n = 7), vasculitis (n = 5), and perivenular infiltrate (n = 4)
  • Similarity of interstitial cystitis to lupus erythematosus.
    Fister GM. J Urol 1938;40:37-51
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